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Home > Conditions A-Z > Hypothyroidism
Home > Help Desk > Health Concern > Section H > Hypothyroidism

Hypothyroidism




   
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Hypothyroidism is a condition in which the thyroid gland fails to function adequately, resulting in reduced levels of thyroid hormone in the body. Cretinism is a type of hypothyroidism that occurs at birth and results in stunted physical growth and mental development. Severe hypothyroidism is called myxedema.

There are many causes of hypothyroidism. Hashimoto’s thyroiditis is an autoimmune disease of the thyroid gland and the second most common cause of hypothyroidism. The most common cause of hypothyroidism is medical treatment, such as surgery or radiation to the thyroid gland, to treat hyperthyroidism (over-activity of the thyroid gland). Some drugs, such as lithium and phenylbutazone, may also induce hypothyroidism. Extreme iodine deficiency, which is rare in the United States, is another possible cause. Failure of the pituitary gland or hypothalamus to stimulate the thyroid gland properly can cause a condition known as secondary hypothyroidism.

Some people with goiter (an enlargement of the thyroid gland) also have hypothyroidism. Goiter can be caused by an iodine deficiency, by eating foods that contain goitrogens (goiter-causing substances), or by other disorders that interfere with thyroid hormone production. In many cases the cause of goiter cannot be determined. While natural therapies may help to some extent, thyroid hormone replacement is necessary for most people with hypothyroidism.

What are the symptoms of hypothyroidism?
The symptoms of hypothyroidism vary from person to person, but commonly include several of the following: fatigue, lethargy, intolerance to cold, constipation, weight gain, depression, excessive menstruation, dry skin, hair loss, and hoarseness. The onset of these symptoms may be so gradual as to evade detection by patient or physician.


How is it treated?
The preferred conventional treatment for hypothyroidism is the synthetic thyroid hormone levothyroxine.


Dietary changes that may be helpful:
Some foods, such as rapeseed (used to make canola oil) and Brassica vegetables ( cabbage, Brussels sprouts, broccoli, and cauliflower), contain natural goitrogens, chemicals that cause the thyroid gland to enlarge by interfering with thyroid hormone synthesis.


Nutritional supplements that may be helpful:
The relationship between iodine and thyroid function is complex. Iodine is required by the body to form thyroid hormone, and iodine deficiency can lead to goiter and hypothyroidism. Severe and prolonged iodine deficiency can potentially lead to serious types of hypothyroidism, such as myxedema or cretinism. It is estimated that one and a half billion people living in 118 countries around the world are at risk for developing iodine deficiency.


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